Associated Chromosomal Abnormalities
Down's syndrome, William's syndrome and Turner syndrome are all chromosomal disorders that have been linked with coeliac disease. The prevalence of coeliac disease in Down's syndrome individuals has been estimated to be around 5%, with the prevalence in both William's syndrome and Turner syndrome also increased when compared with the general population1,2,3.
References
1.Holmes GKT & Catassi C. Coeliac Disease. Health Press 2000
2. Giannottii A, Tiberio G, Castro M et al. Coeliac disease in William's syndrome. J Med Genert 2001;38:767-768
3. Bonamico M, Pasquino AM, Mariani P et al. Prevalence and clinical picture of celiac disease in Turner syndrome. J Clin Endocrinol Metab 2002;87(12):5495-5498
To select summaries of relevant clinical papers in this area please use the right-hand menu.